Truncal varicose veins – therapy with Sealing Foam

Truncal varicose veins – therapy with sealing foam effective?

Microfoam has been used since the beginning of the 2000’s for the treatment of truncal varicose veins. However, the idea of ​​sealing varicose veins is not new. Already in the 1920’s, varicose veins were sealed with glucose solution.

Also the Nestor of the sclerotherapy in Germany, Paul Linser, changed after his move to Berlin from the saline for sclerosis to sealing with sugar solutions.



Paul Linser

At the end of the 1920’s, even at Ferdinand Sauerbruch’s surgery department of the university hospital Charitè, stripping had been completely eliminated and replaced by sealing therapy with sugar solutions.

Ferdinand Sauerbruch, portrait by Max Lieberman

With the success of sealing veins up from 2011 the idea came up to further develop the microfoam. The sealing of veins has been carried out since the twenties in many German hospitals. The known technical and chemical possibilities, combined with the microfoam therapy practiced since the mid-90s, almost inevitably lead to a combination of these techniques. Sealing Microfoam is one of the possible variations.

Microfoam is known since nearly 80 years

The microfoam for the treatment of varicose veins has been known since 1938. He has established himself in the 90’s as a solid therapy of varicose veins and spider veins. The treatment management of the varicose disease was clearly facilitated and the therapy was gentle. In addition to finding an adhesive component, nothing new had to be developed. There was already clinical experience from the 20’s to 30’s of the last century for sealing varicose veins….

Microfoam Gold standard for treatment of reticular veins and spider veins

Since 2010, the United States Food and Drug Administration (FDA) has also approved microfoam therapy with the use of an aethoxyclerol foam to treat varicose veins and declared it the „gold standard“ for spider veins and reticular vein therapy. In Germany, the first guideline on sclerotherapy was published in 2001. It has been updated in the years 2003, 2007 and 2012 specifically with regard to microfoam therapy.

GSV after therapy with sealing foam

Our results over 33 month sealing foam of truncal varicose veins

Since December 2006, we have successfully used microfoam in 13751 sessions.

In the last 33 months (4/2016 – 01/2019), 3850 sealing microfoam treatments have been performed on Saphenion.

In 291 cases, truncal varicose veins were treated. In 107 cases, these were SSV, 98 patients with GSV, in 86 cases VSAA.

In addition, Giacomini vein or Femoropopliteal vein on the thigh and lower leg was treated in 81 cases. The average age of patients in this therapy group was 43 years (18-83 years).

It was 0.5% – 3% Ethoxisklerol used and foamed with a – since the mid twenties also used in truncal veins – intense adhesive sterile liquid.
The treatment duration was on average 26 minutes. (5 – 48 min), anesthesia was not necessary in any case. Simultaneous therapy on both legs or side branches and spider veins is possible if the maximum amount of microfoam applied in the guidelines for microfoam therapy is not exceeded.

The preoperative diameter of the varicose veins was 4.8 mm (2.3 mm – 10.5 mm). The diameter of the treated veins 9 – 12 months after Sealing Foam was 2.4 mm (0.6 – 7.5 mm).


Therapy success after sealing microfoam

Sealing microfoam therapy was 100% successful in incomplete truncal veins of GSV or SSV. All veins were closed after 33 months. The results for SSV showed a closure rate of 95.3% (102/107 veins). Therapy of complete GSV showed a closure rate of 92.8% (91/98 GSV).

GSV junction after Sealing Foam

Side effects of sealing microfoam

Side effects were extremely rare. In about 5% of all cases we saw a long-term brown discoloration (ecchymosis), in 2 cases, multiple puncture ulcers developed after the therapy. In 8 cases, post op phlebitis had to be treated. A deep vein thrombosis was not seen (thrombosis prophylaxis once intraoperatively).

Also neurological complications were not reported by our patients. These are commonly seen in radical surgical therapy (25-50%) and thermal procedures (about 30%).

In 10 cases an intensive migraine attack had to be treated.

Hardening in the vein course and strand feeling along the treated vein have been described frequently, also soreness feeling or similar phenomenas were called more often.

Our discussion

Sealing foam therapy is also very well suited for the treatment of truncal varicose veins of smaller diameter. We are currently using sealing foam in the case of antecedent veins, if the diameter of the vein in the ultrasound examination does not exceed approx. 5 mm.

The effectiveness of microfoam in the case of truncal varicose vein therapy had already been established by the European Society of Vascular Surgery (ESVS) in its 2015 guidelines.

Compared to radical surgical therapy and the different thermal methods used today, the side effect rate of sealing foam is lower. This is especially important fact for therapy on the lower leg.

Anesthesia is not necessary. Compression stockings we are recommending for 7 -14 days.

Compared to vein glue, a significant cost advantage stands out. However, the vein glue allows the treatment of all truncal varicose veins requiring treatment simultaneously in one session. This is not fully achievable with the sealing foam, since the amount used per session is limited. In addition, the effectiveness of the sealing foam in treatment of the trunk varicose veins compared to the vein glue is very dependent on the vein diameter, the venous pressure and flow in the varicose veins.

On the other hand, however, a therapy of side branches, reticular and spider veins is simultaneously possible.

Our experiences

Sealing foam can also be used for varicose veins of larger diameters, but in our experience a very good therapeutic effect up to a vein diameter of 5 mm is certain.

For all larger diameters, the use of venous glue, laser or radio wave shows a higher closure efficiency.

However, it should also be taken into account that the thermal procedure, especially on the lower leg, can damage peripheral nerves.

The use of sealing foam in the case of truncal varicosis is being consistently pursued by us. With further experience, the individual indication profile can be further sharpened and the patient receives more comprehensive information about their own therapy decision.

Next to the non-thermal venous adhesive we have a second effective – non-thermal, non-tumescent minimally invasive endovenous procedure.

 

Links:

  1. http://www.ejves.com/article/S1078-5884(15)00097-0/abstract
  2. http://www.ejves.com/article/S1078-5884(15)00097-0/abstract
  3. http://www.der-niedergelassene-arzt.de/fileadmin/user_upload/zeitschriften/vasomed/Artikel_PDF/2017/01-2017/Murena.pdf
  4. http://www.ncbi.nlm.nih.gov/pubmed/26557230
  5. http://www.phlebology.de/leitlinien-der-dgp-mainmenu/280-leitlinie-zur-diagnostik-und-therapie-der-krampfadererkrankung
  6. http://gesundheitsnews.imedo.de/news/1017861-krampfadern-minimalinvasive-therapien-auf-dem-vormarsch
  7. http://van den Bos R. et al. : Metaanalyse randomisierter klinischer Studien und Fallserien, J. Vasc. Surg., 2008, Aug.8
  8. https://www.ncbi.nlm.nih.gov/pubmed/28892412
  9. https://www.ncbi.nlm.nih.gov/pubmed/29629358
  10. https://www.der-niedergelassene-arzt.de/praxis/sklerosierungstherapie-von-der-fluessig-zur-schaumveroedung/105,878,573,280/4c7d5327196d06207954826f4defa702/?tx_news_pi1%5Bcategories%5D=22_83_6
  11. https://www.der-niedergelassene-arzt.de/praxis/bewegung-nach-der-sklerotherapie/category-6/105,878,528/236cc062f2899eacff25a57524e32e7a/
  12. Bier,Braun Kümmel: Chirurgische Operationslehre, begründet. von F. Sauerbruch; Johann Ambrosius Barth, Leipzig; 1958
  13. http://Lahl w und Zierau UT:  http://vascular-endovascular-therapy.imedpub.com/abstract/the-fate-of-saphenaviews-into-the-past-23856.html
  14. http://Zierau U Th: http://vascular-endovascular-therapy.imedpub.com/the-endovenous-eighteens18-years-endovenous-therapy-of-truncal-varicose-veins.php?aid=23424
  15. http://Zierau U Th: http://innovationinfo.org/scholarly-journal-of-surgery/article_inpress/76-month-long-time-experience-with-the-VenaSeal—system-in-treatment-of-truncal-varicose-veins
  16. http://Zierau U Th: http://vascular-endovascular-therapy.imedpub.com/the-endovenous-eighteens18-years-endovenous-therapy-of-truncal-varicose-veins.php?aid=23424

Hinterlasse einen Kommentar

Deine E-Mail-Adresse wird nicht veröffentlicht. Erforderliche Felder sind mit * markiert.